Chapman & Hall/CRC biostatistics seriesDesign and Analysis of Clinical Trials for Predictive Medicine9781466558168, 1466558164

Author : Shigeyuki Matsui; Marc Buyse; Richard Simon
Description:An emerging clinical trials paradigm for predictive medicine involves the development of molecular diagnostics to enable the prediction of the effects of treatment or outcomes of individual patients. This book offers statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics. The book explains how to identify molecular biomarkers using DNA microarrays, validate the developed biomarkers, and confirm their clinical utility in randomized clinical trials. Read more...
Categories: Biology Biostatistics
Year :2015
Publisher : CRC Press
Language : English
N° Of Pages : 394 p.
File Info : pdf 6 Mb