Current Topics in Membranes 48Membrane Permeability100 Years since Ernest Overton [1ed.]0121533484, 9780121533489, 9780080585192

Author : Davld W. Deamer, Arnost Kleinzeller and Douglas M. Fambrough (Eds.)
Description:Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Key Features * Provides an historical perspective of Overton's contributions to the theory of narcosis * Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion
Categories: Biology Biochemistry
Year :1999
Publisher : Academic Press
Language : English
N° Of Pages : ii-xvi, 1-423[443]
File Info : pdf 24 Mb