Methods in Molecular BiologyDNA-Protein Interactions. Principles and Protocols [1sted.]9780896032569, 0896032566

Author : G. Geoff Kneale
Description:The clear and easy-to-follow protocols collected here illuminate the molecular basis of protein-nucleic acid interactions. Use them successfully to reveal the location of the DNA binding site, the strength and specificity of a binding, the identities of individual groups on the actual bases involved in binding, and the specific amino acid residues of the protein that interact with the DNA. Some of the techniques can even be used to identify previously unknown DNA binding proteins from crude cell extracts, thus empowering you to make groundbreaking advances in your work.
Categories: Biology Biotechnology
Year :1994
Publisher : Humana Press
Language : English
N° Of Pages : 424
File Info : pdf 27 Mb