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Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases (Wiley – Interscience Series on Mass Spectrometry) [1ed.]0471723452, 9780471723455

Author : Isabella Dalle-Donne, Andrea Scaloni, D. Allan Butterfield, Dominic M. Desiderio, Nico M. Nibbering
Description:Methodology and applications of redox proteomicsThe relatively new and rapidly changing field of redox proteomics has the potential to revolutionize how we diagnose disease, assess risks, determine prognoses, and target therapeutic strategies for people with inflammatory and aging-associated diseases. This collection brings together, in one comprehensive volume, a broad array of information and insights into normal and altered physiology, molecular mechanisms of disease states, and new applications of the rapidly evolving techniques of proteomics.Written by some of the finest investigators in this area, Redox Proteomics: From Protein Modifications to Cellular Dysfunction and Diseases examines the key topics of redox proteomics and redox control of cellular function, including:* The role of oxidized proteins in various disorders* Pioneering studies on the development of redox proteomics* Analytical methodologies for identification and structural characterization of proteins affected by oxidative/nitrosative modifications* The response and regulation of protein oxidation in different cell types* The pathological implications of protein oxidation for conditions, including asthma, cardiovascular disease, diabetes, preeclampsia, and Alzheimer's diseaseDistinguished by its in-depth discussions, balanced methodological approach, and emphasis on medical applications and diagnosis development, Redox Proteomics is a rich resource for all professionals with an interest in proteomics, cellular physiology and its alterations in disease states, and related fields.
Categories: Biology Molecular
Year :2006
Publisher : Wiley-Interscience
Language : English
N° Of Pages : 977
File Info : pdf 14 Mb

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