Ribosome-inactivating Proteins: Ricin and Related Proteins1118125657, 9781118125656

Author : Fiorenzo Stirpe, Douglas A. Lappi
Description:This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.
Categories: Biology Molecular
Year :2014
Publisher : Wiley-Blackwell
Language : English
N° Of Pages : xii+296
File Info : pdf 7 Mb